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Title: A Passive Micromixer for Bioanalytical Applications
Authors: Kefala, IK
Papadopoulos, VE
Kokkoris, G
Karpou, G
Moschou, D
Papadakis, G
Tserepi, A
4th Micro and Nano Flows Conference (MNF2014)
Keywords: Passive Micromixer;Microflow;Split and recombine;Lab-on-a-chip;LoC;FPC technology;Dean Vortices
Issue Date: 2014
Publisher: Brunel University London
Citation: 4th Micro and Nano Flows Conference, University College London, UK, 7-10 September 2014, Editors CS König, TG Karayiannis and S. Balabani
Series/Report no.: ID 152
Abstract: Three passive micromixers with different geometries, i.e. zigzag, spiral, and split and merge (SaM) with labyrinthine channels, are compared with respect to their mixing efficiency by means of a computational study. The specifications are imposed from flexible printed circuit (FPC) technology which is used for their fabrication and from the applications to be implemented, i.e. the mixing of biochemical reagents. The computations include the numerical solution of continuity, Navier-Stokes, and mass conservation equations in 3d by ANSYS Fluent. The highest mixing efficiency is calculated for the SaM micromixer with the labyrinthine channel. Compared to a linear micromixer, the spiral micromixer improves the mixing efficiency by 8%, the zigzag by 11%, and the SaM by 92%; the diffusion coefficient of the biomolecule is 10-10 m2/s, the Reynolds number is 0.5, and the volume of each micromixer is 2.54 μl. The best of the three designs is realized by FPC technology and is experimentally evaluated by fluorescence microscopy.
Description: This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute, ASME Press, LCN London Centre for Nanotechnology, UCL University College London, UCL Engineering, the International NanoScience Community,
ISBN: 978-1-908549-16-7
Appears in Collections:Brunel Institute for Bioengineering (BIB)
The Brunel Collection

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