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Title: Innate immunity and neuroinflammation
Authors: Shastri, A
Bonifati, DM
Kishore, U
Issue Date: 2013
Publisher: Hindawi Publishing Corporation
Citation: Mediators Inflamm, 2013, 342931, 2013
Abstract: Inflammation of central nervous system (CNS) is usually associated with trauma and infection. Neuroinflammation occurs in close relation to trauma, infection, and neurodegenerative diseases. Low-level neuroinflammation is considered to have beneficial effects whereas chronic neuroinflammation can be harmful. Innate immune system consisting of pattern-recognition receptors, macrophages, and complement system plays a key role in CNS homeostasis following injury and infection. Here, we discuss how innate immune components can also contribute to neuroinflammation and neurodegeneration.
Description: Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
ISSN: 0962-9351
Appears in Collections:Biological Sciences
Dept of Life Sciences Research Papers

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