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dc.contributor.authorSoulis, JV-
dc.contributor.authorFytanidis, DK-
dc.contributor.authorSeralidou, KV-
dc.contributor.authorKaragkiozaki, VC-
dc.contributor.authorGiannoglou, GD-
dc.contributor.author3rd Micro and Nano Flows Conference (MNF2011)-
dc.identifier.citation3rd Micro and Nano Flows Conference, Thessaloniki, Greece, 22-24 August 2011en_US
dc.descriptionThis paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, Aristotle University of Thessaloniki, University of Thessaly, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute.en_US
dc.description.abstractCurrent computational analysis results quantify Wall Shear Stress (WSS) and its impact on Low Density Lipoprotein (LDL) concentration of a fully deployed straight artery stent. Atherosclerosis shows predilection in arterial regions with hemodynamic particularities, as local disturbances of WSS in space, and locally high concentrations of lipoprotein. The WSS and subsequently the LDL distribution are important indicators of stent performance. A typical 6.0 mm diameter straight stented artery is used to elucidate the WSS and the LDL transport under steady flow conditions treating the blood as a non-Newtonian fluid. Struts are 50.0 % embedded into the arterial wall. Emphasis is placed in the LDL distribution at the upstream and downstream flow regions of each strut intersection. Reduced WSS values are observed towards outlet. At the strut intersections, high WSS values are observed possibly causing platelet activation. Prone to plaque development are flow regions located at specific strut intersections (mostly at the vicinity of the curved struts) where increased LDL concentration is observed. The maximum LDL concentration over the stented artery reaches a value of 3.8 % higher than that at the entrance. The concentration at distal to any strut region was higher than proximal to the strut.en_US
dc.publisherBrunel Universityen_US
dc.subjectWall shear stressen_US
dc.subjectLDL transporten_US
dc.subjectStented arteryen_US
dc.titleWall shear stress and low density lipoprotein concentration in stented arteriesen_US
dc.typeConference Paperen_US
Appears in Collections:Brunel Institute for Bioengineering (BIB)
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