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Title: Multicompartmental poroelastic modelling for CSF production and circulation
Authors: Vardakis, JC
Tully, B
Byrne, J
Ventikos, Y
3rd Micro and Nano Flows Conference (MNF2011)
Keywords: Cerebrospinal fluid;Choroid plexus;Hydrocephalus;Porous media;Ventriculostomy;MRI
Issue Date: 2011
Publisher: Brunel University
Citation: 3rd Micro and Nano Flows Conference, Thessaloniki, Greece, 22-24 August 2011
Abstract: This study proposes the implementation of a Multiple-Network Poroelastic Theory (MPET) model for the purpose of investigating in detail the transport of water within the cerebral environment. The advantage of using the MPET representation is that it accounts for fluid transport between CSF, brain parenchyma and cerebral blood. They key novelty in the model discussed in the present study is the amalgamation of anatomically accurate Choroid Plexus regions, with their individual feeding arteries. This model is used to demonstrate the impact of aqueductal stenosis and atresia of the Foramina of Luschka and Magendie on the cerebral ventricles. The possible implications of treating such a condition with the aid of endoscopic third ventriculostomy are investigated and discussed.
Description: This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, Aristotle University of Thessaloniki, University of Thessaly, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute.
ISBN: 978-1-902316-98-7
Appears in Collections:Brunel Institute for Bioengineering (BIB)
The Brunel Collection

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