Please use this identifier to cite or link to this item: http://buratest.brunel.ac.uk/handle/2438/5099
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dc.contributor.authorBerthod, A-
dc.contributor.authorMaryutina, T-
dc.contributor.authorSpivakov, B-
dc.contributor.authorShpigun, O-
dc.contributor.authorSutherland, IA-
dc.date.accessioned2011-05-10T10:21:22Z-
dc.date.available2011-05-10T10:21:22Z-
dc.date.issued2009-
dc.identifier.citationPure and Applied Chemistry, 81(2): 355 - 387, 2009en_US
dc.identifier.issn0033-4545-
dc.identifier.urihttp://www.iupac.org/publications/pac/81/2/0355/en
dc.identifier.urihttp://bura.brunel.ac.uk/handle/2438/5099-
dc.description© 2009 IUPACen_US
dc.description.abstractCountercurrent chromatography (CCC) is a generic term covering all forms of liquid-liquid chromatography that use a support-free liquid stationary phase held in place by a simple centrifugal or complex centrifugal force field. Biphasic liquid systems are used with one liquid phase being the stationary phase and the other being the mobile phase. Although initiated almost 30 years ago, CCC lacked reliable columns. This is changing now, and the newly designed centrifuges appearing on the market make excellent CCC columns. This review focuses on the advantages of a liquid stationary phase and addresses the chromatographic theory of CCC. The main difference with classical liquid chromatography (LC) is the variable volume of the stationary phase. There are mainly two different ways to obtain a liquid stationary phase using centrifugal forces, the hydrostatic way and the hydrodynamic way. These two kinds of CCC columns are described and compared. The reported applications of CCC in analytical chemistry and comparison with other separation and enrichment methods show that the technique can be successfully used in the analysis of plants and other natural products, for the separation of biochemicals and pharmaceuticals, for the separation of alkaloids from medical herbs, in food analysis, etc. On the basis of the studies of the last two decades, recommendations are also given for the application of CCC in trace inorganic analysis and in radioanalytical chemistry.en_US
dc.languageEN-
dc.language.isoenen_US
dc.publisherInternational Union of Pure and Applied Chemistryen_US
dc.subjectCountercurrent chromatographyen_US
dc.subjectLiquid-liquid chromatographyen_US
dc.subjectLiquid stationary phaseen_US
dc.subjectTrace inorganic analysisen_US
dc.subjectRadioanalytical chemistryen_US
dc.subjectIUPAC Analytical Chemistry Divisionen_US
dc.titleCountercurrent chromatography in analytical chemistry (IUPAC technical report)en_US
dc.typeTechnical Reporten_US
dc.identifier.doihttp://dx.doi.org/10.1351/PAC-REP-08-06-05-
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pubs.organisational-group/Brunel/Research Centres/BIAS-
pubs.organisational-group/Brunel/School of Health Sciences and Social Care-
pubs.organisational-group/Brunel/School of Health Sciences and Social Care/BIAS-
pubs.organisational-group/Brunel-
pubs.organisational-group/Brunel/Brunel (Active)-
pubs.organisational-group/Brunel/Brunel (Active)/Research Centres-
pubs.organisational-group/Brunel/Research Centres-
pubs.organisational-group/Brunel/Research Centres/ABC-
pubs.organisational-group/Brunel/Research Centres/BIAS-
pubs.organisational-group/Brunel/School of Health Sciences and Social Care-
pubs.organisational-group/Brunel/School of Health Sciences and Social Care/BIAS-
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