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dc.contributor.authorAllison, R-
dc.contributor.authorKilbride, C-
dc.contributor.authorChynoweth, J-
dc.contributor.authorCreanor, S-
dc.contributor.authorFrampton, I-
dc.contributor.authorMarsden, J-
dc.identifier.citationArchives of Physical Medicine and Rehabilitation, (2017)en_US
dc.description.abstractObjective: To establish the longitudinal profile of impairments of body functions and activity limitations of the arm, and evaluate potential predictors of difficulty caring for the profoundly-affected arm post-stroke. Design: Prospective cohort study. Setting: Three UK stroke services. Participants: People unlikely to regain functional use of the arm (N=155) were recruited at 2-4 weeks post-stroke, and followed up at 3, 6 and 12 months. Potential predictors at baseline were hypertonicity, pain, motor control, mood, sensation/perception, age and stroke severity. Interventions: NA Main Outcome Measures: Difficulty caring for the arm (LASIS), pain, hypertonicity, range of movement, arm function and skin integrity. Multi-variable linear regression identified the best fitting model for predicting LASIS at 12 months. Results: One hundred and ten participants (71%) were reviewed at one year. There was a large variation in the profile of arm functions and activity limitations. Inability or severe difficulty caring for the arm affected 29% of participants. Hypertonicity developed in 77%, with severe hypertonicity present in 25%. Pain was reported by 65%, 94% developed shoulder contracture and 6% had macerated skin. Difficulty caring for the arm increased with age, greater level of hypertonicity and stroke classification; collectively these factors accounted for 33% of the variance in LASIS. Conclusions: At one year post-stroke, there was a high incidence of impairments of body functions and activity limitations in people with a profoundly-affected arm. Individual profiles were very variable and although some pre-disposing factors have been identified, it remains difficult to predict who is at greatest risk.en_US
dc.description.sponsorshipThis study was funded by a grant from Torbay Medical Research Fund (TOR 106).en_US
dc.subjectUpper limben_US
dc.titleWhat is the longitudinal profile of impairments and can we predict difficulty caring for the profoundly-affected arm in the first year post-stroke?en_US
dc.relation.isPartOfArchives of Physical Medicine and Rehabilitation-
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