Please use this identifier to cite or link to this item: http://buratest.brunel.ac.uk/handle/2438/12456
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dc.contributor.authorDe Cock, M-
dc.contributor.authorDe Boer, MR-
dc.contributor.authorLamoree, M-
dc.contributor.authorLegler, J-
dc.contributor.authorVan de Bor, M-
dc.date.accessioned2016-04-07T08:39:35Z-
dc.date.available2014-07-01-
dc.date.available2016-04-07T08:39:35Z-
dc.date.issued2014-
dc.identifier.citationInternational Journal of Environmental Research and Public Health,11, (7):, pp. 7001 - 7021, (2014)en_US
dc.identifier.issn1660-4601-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113857/-
dc.identifier.urihttp://bura.brunel.ac.uk/handle/2438/12456-
dc.description.abstractGrowth in the first year of life may already be predictive of obesity later in childhood. The objective was to assess the association between prenatal exposure to various endocrine disrupting chemicals (EDCs) and child growth during the first year. Dichlorodiphenyldichloroethylene (DDE), mono(2-ethyl-5-carboxypentyl)phthalate (MECPP), mono(2-ethyl-5-hydroxyhexyl)phthalate (MEHHP), mono(2-ethyl-5-oxohexyl)phthalate (MEOHP), polychlorinated biphenyl-153, perfluorooctanesulfonic acid, and perfluorooctanoic acid were measured in cord plasma or breast milk. Data on weight, length, and head circumference (HC) until 11 months after birth was obtained from 89 mother-child pairs. Mixed models were composed for each health outcome and exposure in quartiles. For MEOHP, boys in quartile 1 had a higher BMI than higher exposed boys (p = 0.029). High DDE exposure was associated with low BMI over time in boys (0.8 kg/m2 difference at 11 m). Boys with high MECPP exposure had a greater HC (1.0 cm difference at 11 m) than other boys (p = 0.047), as did girls in the second quartile of MEHHP (p = 0.018) and DDE (p < 0.001) exposure. In conclusion, exposure to phthalates and DDE was associated with BMI as well as with HC during the first year after birth. These results should be interpreted with caution though, due to the limited sample size.en_US
dc.format.extent7001 - 7021 (21)-
dc.languageEnglish-
dc.language.isoenen_US
dc.publisherMDPI AGen_US
dc.subjectEndocrine disruptionen_US
dc.subjectPrenatal exposureen_US
dc.subjectBMIen_US
dc.subjectHead circumferenceen_US
dc.subjectEarly childhooden_US
dc.titleFirst year growth in relation to prenatal exposure to endocrine disruptors - A dutch prospective cohort studyen_US
dc.typeArticleen_US
dc.identifier.doihttp://dx.doi.org/10.3390/ijerph110707001-
dc.relation.isPartOfINTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH-
pubs.issue7-
pubs.publication-statusPublished-
pubs.volume11-
Appears in Collections:Dept of Life Sciences Research Papers

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