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Title: A new approach to planning in vitro and in vivo experiments for cardiovascular stents – II. Planning of experiment (abstract)
Authors: Atherton, M
Doorly, DJ
Collins, MW
Issue Date: 2000
Publisher: Elsevier
Citation: Biomedicine & Pharmacotherapy, 54, (8-9): pp. 437 - 470, (2000)
Abstract: Within our overall project to improve the design of stents in terms of reduced rates of re-stenosis, there are three main methods, namely computer simulation and in vitro and in vivo experiments. These methods are closely integrated using contemporary design procedures described below, especially to accommodate patient-to-patient variation. Clinical experience shows that a small variation has considerable effects on flow characteristics of stents and in engineering terms may be described as a ‘geometric risk factor’. The Robust Engineering Design procedure readily incorporates this factor which may thus become a component feature in our experimental planning. We envisage that this approach could be applied to other invasive implants with a view to enhancing their quality.
ISSN: 0753-3322
Appears in Collections:Dept of Mechanical Aerospace and Civil Engineering Research Papers

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