Please use this identifier to cite or link to this item: http://buratest.brunel.ac.uk/handle/2438/10237
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dc.contributor.authorBridger, JM-
dc.coverage.spatialEngland-
dc.coverage.spatialEngland-
dc.date.accessioned2015-02-13T15:42:36Z-
dc.date.available2011-12-
dc.date.available2015-02-13T15:42:36Z-
dc.date.issued2011-
dc.identifier.citationBiochem Soc Trans, 39:6, pp. 1747 - 1751, 2011en_US
dc.identifier.issn1470-8752-
dc.identifier.urihttp://www.biochemsoctrans.org/bst/039/bst0391747.htm-
dc.identifier.urihttp://bura.brunel.ac.uk/handle/2438/10237-
dc.description.abstractThere are an increasing number of studies reporting the movement of gene loci and whole chromosomes to new compartments within interphase nuclei. Some of the movements can be rapid, with relocation of parts of the genome within less than 15 min over a number of microns. Some of these studies have also revealed that the activity of motor proteins such as actin and myosin are responsible for these long-range movements of chromatin. Within the nuclear biology field, there remains some controversy over the presence of an active nuclear acto-myosin motor in interphase nuclei. However, both actin and myosin isoforms are localized to the nucleus, and there is a requirement for rapid and directed movements of genes and whole chromosomes and evidence for the involvement of motor proteins in this relocation. The presence of nuclear motors for chromatin movement is thus an important and timely debate to have.en_US
dc.format.extent1747 - 1751-
dc.format.extent1747 - 1751-
dc.languageeng-
dc.language.isoenen_US
dc.subjectActinsen_US
dc.subjectAnimalsen_US
dc.subjectChromosomesen_US
dc.subjectGenetic Locien_US
dc.subjectHumansen_US
dc.subjectInterphaseen_US
dc.subjectMovementen_US
dc.subjectMyosinsen_US
dc.titleChromobility: the rapid movement of chromosomes in interphase nucleien_US
dc.typeArticleen_US
dc.identifier.doihttp://dx.doi.org/10.1042/BST20110696-
dc.relation.isPartOfBiochem Soc Trans-
dc.relation.isPartOfBiochem Soc Trans-
pubs.issue6-
pubs.issue6-
pubs.volume39-
pubs.volume39-
pubs.organisational-data/Brunel-
pubs.organisational-data/Brunel/Brunel Staff by College/Department/Division-
pubs.organisational-data/Brunel/Brunel Staff by College/Department/Division/College of Health and Life Sciences-
pubs.organisational-data/Brunel/Brunel Staff by College/Department/Division/College of Health and Life Sciences/Dept of Life Sciences-
pubs.organisational-data/Brunel/Brunel Staff by College/Department/Division/College of Health and Life Sciences/Dept of Life Sciences/Biological Sciences-
pubs.organisational-data/Brunel/Brunel Staff by Institute/Theme-
pubs.organisational-data/Brunel/Brunel Staff by Institute/Theme/Institute of Environmental, Health and Societies-
pubs.organisational-data/Brunel/Brunel Staff by Institute/Theme/Institute of Environmental, Health and Societies/Synthetic Biology-
pubs.organisational-data/Brunel/University Research Centres and Groups-
pubs.organisational-data/Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups-
pubs.organisational-data/Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups/Brunel Institute for Ageing Studies-
pubs.organisational-data/Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups/Brunel Institute of Cancer Genetics and Pharmacogenomics-
pubs.organisational-data/Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups/Centre for Systems and Synthetic Biology-
Appears in Collections:Biological Sciences
Dept of Life Sciences Research Papers

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