Please use this identifier to cite or link to this item: http://buratest.brunel.ac.uk/handle/2438/10141
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dc.contributor.authorRyan, JM-
dc.contributor.authorCrowley, VE-
dc.contributor.authorHensey, O-
dc.contributor.authorMcGahey, A-
dc.contributor.authorGormley, J-
dc.date.accessioned2015-02-06T12:07:27Z-
dc.date.available2014-04-14-
dc.date.available2015-02-06T12:07:27Z-
dc.date.issued2014-
dc.identifier.citationArchives of Physical Medicine and Rehabilitation, 95(8): (2014)en_US
dc.identifier.issn0003-9993-
dc.identifier.urihttp://www.sciencedirect.com/science/article/pii/S0003999314002809-
dc.identifier.urihttp://bura.brunel.ac.uk/handle/2438/10141-
dc.descriptionThis article has been made available through the Brunel Open Access Publishing Fund.-
dc.description.abstractObjective: To report the prevalence of cardiometabolic risk factors in a cohort of adults with cerebral palsy (CP) and to investigate the ability of anthropometric measures to predict these factors. Design: Cross-sectional study. Setting: Testing took place in a laboratory setting. Participants: Adults with CP (NZ55; mean age, 37.5 13.3y; Gross Motor Function Classification System levels, IeV) participated in this study. Interventions: Not applicable. Main Outcome Measures: Total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, glucose, insulin, and C-reactive protein levels were measured from a fasting venous blood sample. Insulin resistance was calculated using the Homeostasis Model Assessment (HOMA-IR) index. Blood pressure, body mass index (BMI), waist circumference (WC), waist-hip ratio, and waist-height ratio were also measured. The metabolic syndrome (MetS) was defined according to the 2009 Joint Interim Statement. Results: The prevalence of the MetS was 20.5% in ambulatory adults and 28.6% in nonambulatory adults. BMI was associated with HOMA-IR only (bZ.451; P<.01). WC was associated with HOMA-IR (bZ.480; P<.01), triglycerides (bZ.450; P<.01), and systolic blood pressure (bZ.352; P<.05). Receiver operating characteristic curve analysis revealed that WC provided the best indication of hypertensive blood pressure, dyslipidemia, HOMA-IR, and the presence of multiple risk factors (area under the curve, .713e.763). Conclusions: A high prevalence of the MetS was observed in this relatively young sample of adults with CP. WC was a better indicator of a number of risk factors than was BMI and presents as a clinically useful method of screening for cardiometabolic risk among adults with CP.en_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectCardiometabolic risken_US
dc.subjectCerebral palsy (CP)en_US
dc.titleWaist circumference provides an indication of numerous cardiometabolic risk factors in adults with cerebral palsyen_US
dc.typeArticleen_US
dc.identifier.doihttp://dx.doi.org/10.1016/j.apmr.2014.03.029-
dc.relation.isPartOfArchives of Physical Medicine and Rehabilitation-
dc.relation.isPartOfArchives of Physical Medicine and Rehabilitation-
pubs.organisational-data/Brunel-
pubs.organisational-data/Brunel/Brunel Staff by College/Department/Division-
pubs.organisational-data/Brunel/Brunel Staff by College/Department/Division/College of Health and Life Sciences-
pubs.organisational-data/Brunel/Brunel Staff by College/Department/Division/College of Health and Life Sciences/Dept of Clinical Sciences-
pubs.organisational-data/Brunel/Brunel Staff by College/Department/Division/College of Health and Life Sciences/Dept of Clinical Sciences/Physiotherapy-
pubs.organisational-data/Brunel/Brunel Staff by Institute/Theme-
pubs.organisational-data/Brunel/Brunel Staff by Institute/Theme/Institute of Environmental, Health and Societies-
pubs.organisational-data/Brunel/Brunel Staff by Institute/Theme/Institute of Environmental, Health and Societies/Healthy Ageing-
Appears in Collections:Biological Sciences
Brunel OA Publishing Fund
Dept of Life Sciences Research Papers

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