Please use this identifier to cite or link to this item: http://buratest.brunel.ac.uk/handle/2438/9279
Title: Mechanical characterisation of reticulated albumin capsule membranes
Authors: Gires, PY
Salsac, AV
Leclerc, E
Edwards-Lévy, F
Barthès-Biesel, D
4th Micro and Nano Flows Conference (MNF2014)
Keywords: Microfluidic;Capsule;Membrane;Mechanical properties
Issue Date: 2014
Publisher: Brunel University London
Citation: 4th Micro and Nano Flows Conference, University College London, UK, 7-10 September 2014, Editors CS König, TG Karayiannis and S. Balabani
Series/Report no.: ID 20
Abstract: We used a microfluidic technique in order to study the mechanical properties of cross-linked albumin capsule membranes. The capsules were produced from aqueous human serum albumin (HSA) solutions with concentrations of 15%, 20%, 25% and 30% (w/v). The radii were in the range 55-80 m. We find that the capsules follow the neo-Hookean law, which is strain-softening and depends on one parameter, the surface shear modulus. A possible pre-inflation effect due to osmolarity is accounted for by imposing various values of pre-inflation. Small values of pre-inflation are sufficient to fit the data, which indicates that the capsule membrane is under small osmotic stress. Accounting for pre-inflation changes only slightly the surface shear elastic modulus of the membrane. Whatever the pre-inflation ratio, the shear modulus sharply increases with the HSA concentration from a low-value plateau.
Description: This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute, ASME Press, LCN London Centre for Nanotechnology, UCL University College London, UCL Engineering, the International NanoScience Community, www.nanopaprika.eu.
URI: http://bura.brunel.ac.uk/handle/2438/9279
ISBN: 978-1-908549-16-7
Appears in Collections:Brunel Institute for Bioengineering (BIB)
The Brunel Collection

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