Please use this identifier to cite or link to this item: http://buratest.brunel.ac.uk/handle/2438/8995
Title: Unilateral versus bilateral upper limb training after stroke: The upper limb training after stroke clinical trial
Authors: van Delden, AL
Peper, CE
Nienhuys, KN
Zijp, NI
Beek, PJ
Kwakkel, G
Keywords: Rehabilitation;Stroke;Upper extremity
Issue Date: 2013
Publisher: American Heart Association
Citation: Stroke, 44(9), 2613 - 2616, 2013
Abstract: Background and Purpose — Unilateral and bilateral training protocols for upper limb rehabilitation after stroke represent conceptually contrasting approaches with the same ultimate goal. In a randomized controlled trial, we compared the merits of modified constraint-induced movement therapy, modified bilateral arm training with rhythmic auditory cueing, and a dose-matched conventional treatment. Modified constraint-induced movement therapy and modified bilateral arm training with rhythmic auditory cueing targeted wrist and finger extensors, given their importance for functional recovery. We hypothesized that modified constraint-induced movement therapy and modified bilateral arm training with rhythmic auditory cueing are superior to dose-matched conventional treatment. Methods — Sixty patients, between 1 to 6 months after stroke, were randomized over 3 intervention groups. The primary outcome measure was the Action Research Arm test, which was conducted before, directly after, and 6 weeks after intervention. Results — Although all groups demonstrated significant improvement on the Action Research Arm test after intervention, which persisted at 6 weeks follow-up, no significant differences in change scores on the Action Research Arm test were found between groups postintervention and at follow-up. Conclusions — Modified constraint-induced movement therapy and modified bilateral arm training with rhythmic auditory cueing are not superior to dose-matched conventional treatment or each other in improving upper limb motor function 1 to 6 months after stroke. Clinical Trial Registration — URL: http://www.trialregister.nl. Unique identifier: NTR1665.
Description: This article is available open access through the publisher’s website at the link below. Copyright © 2013 American Heart Association, Inc.
URI: http://stroke.ahajournals.org/content/44/9/2613
http://bura.brunel.ac.uk/handle/2438/8995
DOI: http://dx.doi.org/10.1161/STROKEAHA.113.001969
ISSN: 1524-4628
Appears in Collections:Sport
Dept of Life Sciences Research Papers

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