Please use this identifier to cite or link to this item: http://buratest.brunel.ac.uk/handle/2438/7771
Title: Neural activation and functional connectivity during motor imagery of bimanual everyday actions
Authors: Szameitat, AJ
McNamara, A
Shen, S
Sterr, A
Keywords: Brain mapping;Hand;Humans;Magnetic resonance imaging;Motor cortex;Motor skills;Neural pathways;Parietal lobe
Issue Date: 2012
Publisher: Public Library of Science
Citation: PLoS One, 7(6), e38506, 2012
Abstract: Bimanual actions impose intermanual coordination demands not present during unimanual actions. We investigated the functional neuroanatomical correlates of these coordination demands in motor imagery (MI) of everyday actions using functional magnetic resonance imaging (fMRI). For this, 17 participants imagined unimanual actions with the left and right hand as well as bimanual actions while undergoing fMRI. A univariate fMRI analysis showed no reliable cortical activations specific to bimanual MI, indicating that intermanual coordination demands in MI are not associated with increased neural processing. A functional connectivity analysis based on psychophysiological interactions (PPI), however, revealed marked increases in connectivity between parietal and premotor areas within and between hemispheres. We conclude that in MI of everyday actions intermanual coordination demands are primarily met by changes in connectivity between areas and only moderately, if at all, by changes in the amount of neural activity. These results are the first characterization of the neuroanatomical correlates of bimanual coordination demands in MI. Our findings support the assumed equivalence of overt and imagined actions and highlight the differences between uni- and bimanual actions. The findings extent our understanding of the motor system and may aid the development of clinical neurorehabilitation approaches based on mental practice.
Description: © 2012 Szameitat et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
URI: http://www.ncbi.nlm.nih.gov/pubmed/22701655
http://bura.brunel.ac.uk/handle/2438/7771
DOI: http://dx.doi.org/10.1371/journal.pone.0038506
ISSN: 1932-6203
Appears in Collections:Psychology
Dept of Life Sciences Research Papers

Files in This Item:
File Description SizeFormat 
Fulltext.pdf327.99 kBAdobe PDFView/Open


Items in BURA are protected by copyright, with all rights reserved, unless otherwise indicated.