Please use this identifier to cite or link to this item: http://buratest.brunel.ac.uk/handle/2438/3381
Title: Diclofenac solution (Pennsaid) in the management of osteoarthritis of the knee : Patient implications
Authors: Banning, M
Issue Date: 2009
Publisher: Chinese Medical Association
Citation: Chinese Journal of Internal Medicine. In press
Abstract: Topical diclofenac sodium (pennsaid) is a non-steroidal-anti- inflammatory drug that is used to manage the recurrent pain and symptoms of osteoarthritis of the knee. Pennsaid is applied topically, absorbed cutaneously and concentrates locally at the site of application. Tugwell et al. [54] has shown that pennsaid is as efficacious as oral diclofenac as a mode of pain relief without systemic effects. The most common side effect induced by pennsaid is the development of dry skin at the site of application. This is caused by dimethyl sulfoxide which is the vehicle used in the pennsaid formulation. Dimethyl sulfoxide dissolves the natural oils in the skin causing dryness.
URI: http://bura.brunel.ac.uk/handle/2438/3381
ISSN: 0578-1426
Appears in Collections:Community Health and Public Health
Dept of Clinical Sciences Research Papers

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