Please use this identifier to cite or link to this item: http://buratest.brunel.ac.uk/handle/2438/10335
Title: Effect of low voltage AC fields on cardiovascular implants
Authors: Kothandaraman, A
Anson, T
Reynolds, A
Keywords: AC;BMS;Cardiovascular;DES;Electric field;Endothelial cell;Implants;Late stent thrombosis;Red blood cell;Restenosis;Stent
Issue Date: 2015
Publisher: Elsevier Ltd
Citation: Materials Science and Engineering C, 46: 497 - 503, (1 January 2015)
Abstract: Coronary Artery Stents have been the preferred form of treatment for vascular occlusive disease, due to the minimally invasive surgical procedure, post-operative recovery time and cost, when compared to open coronary bypass surgery. The cellular response upon applying an AC electric field to type 316LM Stainless Steel stent mimics was investigated in this paper. The highest RBC adhesion was observed at voltages higher than 88 mV and lower than 74mV. Their unique alignment along the lines of fracture on the stent surface at 88 mV was a phenomenon caused by an increase in electrical conductivity in these regions. Being able to control RBC adhesion may have various clinical implications such as inhibition of thrombus formation, and provide a basis to analyse whether electric fields may be applied to cancer therapy as well.
URI: http://www.sciencedirect.com/science/article/pii/S0928493114006547
http://bura.brunel.ac.uk/handle/2438/10335
DOI: http://dx.doi.org/10.1016/j.msec.2014.10.034
ISSN: 0928-4931
Appears in Collections:The Experimental Techniques Centre

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